Impaired irinotecan biotransformation in hepatic microsomal fractions from patients with chronic liver disease
نویسندگان
چکیده
منابع مشابه
Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease
Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation be...
متن کاملMineral Requirements in Children with Chronic Liver Disease
Introduction: Decreased oral intake or impaired function / structure in the gut, such as hypertension port associated with atrophic changes in the protein nutrition - calories can lead to micronutrient deficiencies.This paper examines the status of micronutrients in chronic liver disease in children. Materials and Methods: In this review study databases including proquest, pubmedcentral, scin...
متن کاملMetabolic Disturbances in Children with Chronic Liver Disease
Introduction: Liver disease results in complex pathophysiologic disturbances affecting nutrient digestion, absorption, distribution, storage, and use. This article aimed to present a classification of metabolic disturbances in chronic liver disease in children? Materials and Methods: In this review study databases including proquest, pubmedcentral, scincedirect, ovid, medlineplus were been se...
متن کاملLiver transplantation reverses hypergammaglobulinemia in patients with chronic hepatic failure
INTRODUCTION Sparse data are available about the effect of therapy methods on antibody levels in patients with liver failure. The aim of this study was to determine serum immunoglobulin concentrations in patients with chronic hepatic failure (CHF), acute- (ALF), or acute-on-chronic liver failure (ACLF) and to evaluate the impact of MARS treatment or liver transplantation (LT) on antibody levels...
متن کاملEffects of thymol on non-alcholic hepatic liver induced with chronic immobility in rats
Abstract Background and Aim: Considering the role of oxidative stress on non-alcoholic fatty liver disease and changing lipid profiles, the antioxidant effect of plants and fruits on biochemical indicators was investigated. Thymol is a phenolic monoterpene that has antioxidant properties. According to the above, in this study, the effects of thymol on improving the symptoms of non-alcoholic fa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2010
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2010.03715.x